This book covers the structure and classification of adhesion molecules in relation to signaling pathways and gene expression. It discusses immunohistochemical localization, neutrophil migration, and junctional, functional, and inflammatory adhesion molecules in pathologies such as leukocyte decompression sickness and ischemia reperfusion injury. Highlighting the medical applications of current research, chapters cover diabetes, obesity, and metabolic syndrome; hypoxia; kidney disease; smoking, atrial fibrillation, and heart disease, the brain and dementia; and tumor proliferation. Finally, it looks at molecular imaging and bioinformatics, high-throughput technologies, and chemotherapy.

Feature, Structure and Classification of Adhesion Molecules: An Overview. Immunohistochemical Localization of Adhesion Molecules. Junctional Adhesion Molecules (JAlVIs). Molecular Imaging of Endothelial Adhesion Molecules. Deleterious Roles of Inflammatory Adhesion Molecules during Aging. The PI-3K/Akt-NF-kappa B Signaling Pathway and Hypoxiainduced Mitogenic Factor in Vascular Adhesion Molecule. Gene Expression. Arginine and Adhesion Molecules. Adhesion Molecules in Stem Cells. Adhesion Molecules and Neutrophil Migration. Adhesion Molecules in Leukocytes and their Reactivity. Adhesion Molecules in Decompression Sickness and Ischemia. Reperfusion Injury. Endothelial Adhesion Molecules in Diabetes. Adhesion Molecules in Obesity and Metabolic Syndrome. Weight Loss and Adhesion Molecules. Hypoxia Reperfusion Injury and Adhesion Molecules. Adhesion Molecules in Kidney Disease. Adhesion Molecules and Smoking. Osteoprotegerin and Adhesion Molecules. Adhesion Molecules in Skin. Expression of Cell-Cell Adhesion Molecules in Matrical Tumors of Hairs, Nails, Teeth and Pituitary Gland. Bioinformatics Analysis to Identify Cell Adhesion Molecules in Cancer. Endothelial Cell Adhesion Molecules and Cancer Progression. Adhesion Molecule Phosphorylation in Cancer Chemothenlpy. Adhesion Molecules in Normal Hematopoiesis and Leukemia. Carbamylated Low-density Lipoprotein and Adhesion Molecules. Adhesion Molecules and Oxidized Low-density Lipoprotein. Adhesion Molecules in Atrial Fibrillation. Apolipoproteins and Cell Adhesion Molecules. Marine n-3 Polyunsaturated Fatty Acids and Cellular Adhesion Molecules in Healthy Subjects and in Patients with Ischemic Heart Disease. Soluble Adhesion Molecules in Brain Infarction. Adhesion Molecules in Dementia.